
Decreased tonic current potentiation, but enhanced mIPSCs potentiation, by EtOH in δ subunit-deficient mice. Summary graphs of changes in total charge transfer of averaged mIPSCs (right) and tonic current Ihold (left) before and after EtOH application in δ +/+ and δ −/− DG cells are shown. Each point represents a mean ± SEM value from 6–12 neurons, two mice per group. *p < 0.05 between +/+ and −/− groups; †p < 0.05 from pre-EtOH value (two-way repeated-measures ANOVA). Note the smaller total charge transfer of averaged mIPSCs in DG cells from δ −/− mice. Also note that 10 mm EtOH significantly potentiates mIPSCs from δ −/− but not δ +/+ mice.




