Direct GABAergic and Glycinergic Inhibition of the Substantia Gelatinosa from the Rostral Ventromedial Medulla Revealed by In Vivo Patch-Clamp Analysis in Rats

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Figure 2.
Figure 2.

RVM-GI facilitates sIPSCs in the SG. A, Typical example of the facilitation of sIPSCs induced by RVM-GI (30 nmol). Ba–Bc, Corresponding traces on an expanded time scale in Aa–Ac, respectively. C, Cumulative distributions of interevent intervals (left; p < 0.01) and current amplitudes (right; p < 0.05) for sIPSCs recorded from the same neuron shown in A (2281 and 5801 events in a 200 s period for sIPSCs before and after RVM-GI). Insets, Averages of sIPSC amplitude (amp.) and frequency (freq.), which are normalized to their controls (n = 9). *p < 0.05.

  1. The Journal of Neuroscience vol. 26 no. 6 1787-1794
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