Analysis of behavior on rotarod mice from all groups were tested once a week for latency to fall from an accelerating rotarod (mean and SEM in seconds per week). There was a significant effect of exercise (treadmill running) on the mean latency to fall (in seconds) from the accelerating rotarod, where the asterisk represents significant differnce between the exercise and no exercise groups (F _(3,44) = 9.587; p < 0.0001). Both MPTP plus exercise and saline plus exercise mice performed better on the rotarod compared with the nonexercised groups. There was no significant effect of MPTP on mean latency to fall (F _(3,44) = 0.851; p = 0.504) and no significant interaction between exercise and MPTP on mean latency to fall (F _(3,44) = 0.965; p = 0.435).