Table 1.
Layer II stellate cell spontaneous postsynaptic currents and synaptic responses to focal photo-uncaging of glutamate in layer II medial entorhinal cortex of control and epileptic rats
| Control | Epileptic | |
|---|---|---|
| EPSCs | ||
| n (cells) | 26 | 30 |
| Spontaneous amplitude (pA) | 8.3 ± 0.8 | 9.5 ± 0.6 |
| Spontaneous frequency (Hz) | 3.6 ± 0.6 | 3.9 ± 0.7 |
| Number of sites stimulated per cell | 85 ± 4 | 88 ± 5 |
| Percentage of responding sites | 19 ± 2 | 19 ± 3 |
| Mean individual amplitude (pA) | 15 ± 1 | 14 ± 2 |
| Half-width (ms) | 6.1 ± 0.2 | 6.0 ± 0.2 |
| IPSCs | ||
| n (cells) | 15 | 19 |
| Spontaneous amplitude (pA) | 30 ± 3 | 28 ± 2 |
| Spontaneous frequency (Hz) | 0.10 ± 0.02 | 0.10 ± 0.04 |
| Number of sites stimulated per cell | 88 ± 5 | 90 ± 6 |
| Percentage of responding sites | 14 ± 4 | 2 ± 1** |
| Mean individual amplitude (pA) | 98 ± 14 | 62 ± 15 |
| Half-width (ms) | 15.8 ± 0.2 | n/d |
-
Values represent mean ± SEM **p < 0.005, t test. n/d, Not determined, because the number of events was insufficient for reliable analysis.
