The Role of Nerve- versus Muscle-Derived Factors in Mammalian Neuromuscular Junction Formation

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Figure 6.
Figure 6.

Reduction in AChR cluster number in musk+/− mutants is compensated by overexpression of an agrin transgene in motor neurons. All panels are based on data from a single litter. n = 2 animals each for all genotypes, 11–12 stacks of optical sections taken at 40× in 0.5 μm steps from both hemidiaphragms of each animal. Differences in cluster numbers between musk +/− versus Hb9–agrn;musk+/− and w.t., respectively, are significant (p < 0.01).

  1. The Journal of Neuroscience vol. 28 no. 13 3333-3340
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