Adaptation decreases spike-timing precision in NM in response to simulated physiological inputs. A, Example of a conductance stimulus (bottom), the resulting injected current (middle), and the voltage response (top) in dynamic clamp. B, Cycle PSTH of the early (black) and late (gray) responses. The solid lines are Gaussian fits to the data. C, Firing rate for early and late response (gray crosses, individual cells; black diamonds, group average; n = 13). D, Spike jitter for early and late response. E, Vector strength for early and late response. For C–E, the error bars represent SE (*p < 0.01, paired t test).