Shift from Hippocampal to Neocortical Centered Retrieval Network with Consolidation

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Figure 3.
Figure 3.

Networks that support retrieval of unconsolidated and consolidated memory traces. A, Functional connectivity (PPI) with the posterior hippocampus. The connectivity to the early visual areas, extending to FFA, bilaterally and PPC bilaterally decreased with consolidation. B, Functional connectivity with FFA. Increase with consolidation was observed to the early visual areas bilaterally and the left PPC extending to the motor cortex (top). Decrease with consolidation was observed in the left anterior hippocampus, the left parahippocampal gyrus and the right inferior to middle temporal lobe (bottom). A and B (top) show significant clusters superimposed onto a 3D image viewed from the back side and on intensity projection maps. B (bottom) shows the representative sagittal and coronal slices showing the significant cluster. Blue shows decrease with consolidation and red shows increase with consolidation. The circles in the sagittal and axial intensity projection maps represent the approximate location of the seed regions. Activations are depicted at p < 0.001 uncorrected and cluster size that exceed 90 voxels for all panels, showing the significant clusters. R, Right.

  1. The Journal of Neuroscience vol. 29 no. 32 10087-10093
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