Basal Forebrain Lactate Release and Promotion of Cortical Arousal during Prolonged Waking Is Attenuated in Aging

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Figure 5.
Figure 5.

Correlation of BF lactate release with waking theta. Lactate responses (percentage of pretreatment level; y-axis) in individual samples collected during the SD day (pretreatment and treatment periods; on average, 6 lactate samples were contributed by 1 rat) were matched with corresponding waking theta responses (high-to-low waking theta ratio; percentage difference; x-axis) of the 30 min collection period and plotted separately for each age group: Y (•), M (×), O (○) (nY = 10; nM = 5; nO = 13). Simple regression line is shown for each plot. Statistically significant positive correlation (p < 0.005; Pearson's product moment correlation) was found in the young but not in the middle-aged or old group.

  1. The Journal of Neuroscience vol. 29 no. 37 11698-11707
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