Cerebral monocyte recruitment in day 10 BDR mice is inhibited in the absence of MCP-1/CCL2 or CCR2. Representative flow cytometry profiles from day 10 WT BDR (A) versus MCP-1/CCL2 KO BDR (B) mice. The inserted number shows the percentage of total brain mononuclear cells that are CD45^high CD11b⁺ (i.e., infiltrating monocytes). C, Solid bars represent the percentage of isolated brain mononuclear cells that are CD45^high CD11b⁺ in day 10 WT BDR and MCP-1/CCL2 KO BDR mice. Hatched bars represent the total number of CD45^high CD11b⁺ cells isolated from the brains of day 10 WT BDR and MCP-1/CCL2 KO BDR mice. Error bars represent the mean ± SEM of data from 4 WT BDR and 3 MCP-1/CCL2 KO BDR mice; *p < 0.05 versus WT BDR mice. Representative flow cytometry profiles from day 10 WT BDR (D) versus CCR2 KO BDR (E) mice. The inserted number shows the percentage of total brain mononuclear cells that are CD45^high CD11b⁺. F, Solid bars represent the percentage of total brain mononuclear cells that are CD45^high CD11b⁺ in day 10 WT BDR and CCR2 KO BDR mice. Hatched bars represent the total number of CD45^high CD11b⁺ cells isolated from the brains of day 10 WT BDR and CCR2 KO BDR mice. Bars represent the mean ± SEM of data from 4 WT BDR and 4 CCR2 KO BDR mice; *p < 0.05 versus WT BDR mice.