Burst-Induced Anti-Hebbian Depression Acts through Short-Term Synaptic Dynamics to Cancel Redundant Sensory Signals

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Figure 2.
Figure 2.

Burst-induced long-term depression in ELL pyramidal cells. A , Normalized EPSP peak amplitude averages during control of only presynaptic burst stimulation (4 pulses at 100 Hz) (4-0; n = 2). B , EPSP averages before burst pairing (4 presynaptic and 4 postsynaptic stimulations; gray) and after pairing (black). C , Normalized EPSP peak amplitude averages during pairing protocol at a delay (Δt B) of −25 ms (n = 5). Δt B is defined as the time delay between first pulse of both presynaptic and postsynaptic stimulations. D , The effect of varying Δt B. All time points are normalized EPSP amplitude averages of five to seven cells, except ±100 ms, which has n = 4. Error bars show the SD in A , C , and D .

  1. The Journal of Neuroscience vol. 30 no. 17 6152-6169
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