Table 1.

Changes in Y2 receptor binding in presumed target areas of efferent projections of the CEA after Y2 gene deletion in the CEA

Brain area	% of control ± SEM
Ncl. accumbens, core	80.4 ± 5.00
Ncl. accumbens, shell	64.0 ± 4.96^*
Lateral septum	87.0 ± 6.31
Stria terminalis/bed nucleus of stria terminalis	81.2 ± 3.01^*
Central amygdala	62.5 ± 4.16^***
Lateral hypothalamus	102.4 ± 3.88
Ventral hippocampus (CA1)	95.8 ± 3.80
Periaqueductal gray	96.6 ± 5.21
Locus ceruleus	75.2 ± 3.04^*

[¹²⁵I]hPYY_3-36 was determined 4 weeks after rAAV-Cre injection (n = 16) into the CEA and compared with rAAV-GFP-injected mice (n = 10). Stringent statistical testing by ANOVA and Bonferroni post hoc test was used.
↵*p < 0.05,
↵***p < 0.001.

The Journal of Neuroscience Society for Neuroscience

The Central and Basolateral Amygdala Are Critical Sites of Neuropeptide Y/Y2 Receptor-Mediated Regulation of Anxiety and Depression