T286D decreases AMPAR EPSC, whereas tCaMKII increases it. A , Cell pair recordings were performed from transfected (green) and nontransfected (white) neurons. B , An example of cell pair recordings. Left, Recording from transfected neuron (green arrow). Right, Recording from nontransfected neuron (black arrow). C , The representative traces of AMPAR EPSC from nontransfected and transfected neurons. Calibration: 50 pA, 50 ms. D , T286D decreases AMPAR EPSC, whereas tCaMKII increases it (see Results for details). GFP, Nontransfected = 51.8 ± 8.10 pA, transfected = 46.3 ± 4.65 pA, n = 15, p = 0.33; WT, nontransfected = 58.7 ± 12.02, transfected = 58.9 ± 9.43 pA, n = 7, p = 0.98; T286D, nontransfected = 117.1 ± 16.16 pA, transfected = 39.8 ± 8.59 pA, n = 14, **p < 0.01; tCaMKII, transfected = 112.8 ± 14.36 pA, nontransfected = 75.9 ± 15.47 pA, n = 12, *p < 0.05. For T286D experiments, the stimulation strength was raised to avoid noisy or undetectable small responses due to the depression.