Table 1.
Incidence of electrotonic coupling in mature neuronal somatosensory cortical cultures under different experimental conditions
| Conditions | No. of tested neuronal pairs | No. of coupled neuronal pairs |
|---|---|---|
| WT cultures | ||
| Sham OGD | ||
| Control | 26 | 0 |
| LY379268 (2 μm) | 23 | 4 (i) p = 0.042 |
| LY341495 (2 μm) | 24 | 0 (i) NS |
| OGD | ||
| Nontreated | 32 | 7 (i) p = 0.013 |
| LY379268 (2 μm) | 25 | 10 (i) p = 0.0003, (ii) NS |
| LY341495 (2 μm) | 40 | 1 (i) NS, (ii) p = 0.019 |
| Cx36 knock-out cultures | ||
| Sham OGD | ||
| Control | 15 | 0 |
| LY379268 (2 μm) | 18 | 0 |
| OGD | ||
| Nontreated | 18 | 0 |
-
Statistical analysis was as follows: Fisher's exact probability test, shown relative to control (i) and nontreated plus OGD (ii) in wild-type cultures. NS, Nonsignificant.
