Effects of Digesting Chondroitin Sulfate Proteoglycans on Plasticity in Cat Primary Visual Cortex

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Figure 4.
Figure 4.

Ocular dominance maps in an animal in which the hemisphere ipsilateral to the deprived eye had been injected with chondroitinase. The top row shows the surface view of the dorsal part of the primary visual cortex on the day when the deprived right eye was reopened and the right hemisphere was injected with chondroitinase (white stars mark injection sites) while the left hemisphere was injected with saline (black star). It then shows the ocular dominance map for the nondeprived left eye followed by the ocular dominance map for the deprived right eye. Dark regions indicate areas of response through the stimulated eye. Note that the left and right eye maps are negatives of each other; they are both shown to facilitate visual comparison. The bottom row illustrates cortical surface and left and right eye ocular dominance maps 2 weeks later. Arrows indicate orientation (A, anterior; R, right). Scale bar, 2 mm.

  1. The Journal of Neuroscience vol. 33 no. 1 234-243
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