Interval Tuning in the Primate Medial Premotor Cortex as a General Timing Mechanism

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Figure 2.
Figure 2.

Cell tuning for interval during the SCT and SIRT. A, Responses of an interval-tuned cell with a long preferred interval during the first two elements of the synchronization phase of the SCT in the auditory marker condition. The raster histogram is aligned (red line) to the second tap of the synchronization phase. Black dots correspond to tapping times. B, Responses of the interval-tuned cell in A with a long preferred interval during the SIRT in the auditory condition. The raster histogram is aligned (red line) to the first tap. C, Tuning functions for the cell in A and B, where the mean ± SEM of the discharge rate is plotted as a function of the target interval. The continuous lines correspond to the significant Gaussian fits. SCTa, SCT auditory (blue line); SIRTa, SIRT auditory (red line). D, Histogram of preferred intervals in the visual condition for cells with significant interval tuning during the SCT (median, 842.3 ms). E, Histogram of preferred intervals for tuned cells during the SCT in the auditory condition (median, 835.7 ms). F, Histogram of preferred intervals for tuned cells during the SIRT in the visual condition (median, 821.3 ms). G, Histogram of preferred intervals for tuned cells during the SIRT in the auditory condition (median 808.5 ms). H, Histogram of half-height tuning dispersion of the cells in D (median, 179.4 ms).

  1. The Journal of Neuroscience vol. 33 no. 21 9082-9096
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