Table 2.
FA changes
| White matter regions | Fractional anisotropy | |
|---|---|---|
| Wild type (n = 8) | Itsn1Gt/Gt (n = 10) | |
| Anterior commissure—Pars anterior | 0.68 ± 0.04 | 0.47 ± 0.03** |
| Anterior commissure—Pars posterior | 0.68 ± 0.03 | 0.56 ± 0.03** |
| Arbor vita of the cerebellum | 0.67 ± 0.03 | 0.65 ± 0.03 |
| Cerebellar peduncle—Inferior | 0.89 ± 0.02 | 0.87 ± 0.03 |
| Cerebellar peduncle—Middle | 0.87 ± 0.09 | 0.88 ± 0.05 |
| Cerebellar peduncle—Superior | 0.59 ± 0.02 | 0.54 ± 0.02** |
| Cerebral peduncle | 0.88 ± 0.06 | 0.86 ± 0.03 |
| Corpus callosum | 0.69 ± 0.03 | 0.60 ± 0.02** |
| Cortical spinal tract | 0.66 ± 0.02 | 0.66 ± 0.03 |
| Fasciculus retroflexus | 0.62 ± 0.03 | 0.58 ± 0.02* |
| Fimbria | 0.86 ± 0.02 | 0.72 ± 0.02** |
| Fornix | 0.68 ± 0.03 | 0.54 ± 0.03** |
| Habenular commissure | 0.37 ± 0.04 | 0.30 ± 0.03** |
| Internal capsule | 0.84 ± 0.03 | 0.79 ± 0.02* |
| Lateral olfactory tract | 0.56 ± 0.07 | 0.59 ± 0.04 |
| Mammilothalamic tract | 0.58 ± 0.02 | 0.56 ± 0.02 |
| Medical lemniscus/Medial longitudinal fasciculus | 0.55 ± 0.02 | 0.52 ± 0.02 |
| Optic tract | 0.81 ± 0.05 | 0.75 ± 0.03* |
| Posterior commissure | 0.35 ± 0.02 | 0.35 ± 0.02 |
-
The mean FA values for each region of interest.
-
↵* indicates significance based on an FDR of <0.05 or ** <0.01 with respect to wild type.
