Nicotine Self-Administration Induces CB1-Dependent LTP in the Bed Nucleus of the Stria Terminalis

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Figure 4.
Figure 4.

In Nic-60 d rats, 10 Hz stimulation of ILCx inputs evokes LTP that is CB1 receptor mediated. A, In vivo ILCx stimulation (1 min, 10 Hz) in anesthetized rats. CB1 antagonist AM251 (60 nl, 400 μm) or vehicle was infused into the BNST before stimulation. B, AM251 blocks electrically induced LTP in NIC-60 d rats (Veh, n = 5; AM251, n = 5). *p < 0.05. Data are mean ± SEM.

  1. The Journal of Neuroscience vol. 34 no. 12 4285-4292
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