Naloxone administration prior to mating increased latencies to mount and intromission only on the first day of mating
| Days | Mount latency | Intromission latency | Ejaculation latency | |||
|---|---|---|---|---|---|---|
| Saline | Naloxone | Saline | Naloxone | Saline | Naloxone | |
| 1 | 81 ± 19 | 334 ± 103* | 83 ± 19 | 343 ± 106* | 1378 ± 303 | 1265 ± 317 |
| 2 | 234 ± 117 | 163 ± 83 | 301 ± 119 | 198 ± 79 | 598 ± 79 | 753 ± 198 |
| 3 | 101 ± 40 | 186 ± 63 | 134 ± 41 | 211 ± 68 | 803 ± 229 | 753 ± 163 |
| 4 | 110 ± 78 | 154 ± 105 | 112 ± 79 | 195 ± 105 | 490 ± 122 | 702 ± 140 |
| 5 | 32 ± 19 | 14 ± 4 | 33 ± 19 | 23 ± 11 | 524 ± 106 | 427 ± 75 |
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The effect of naloxone was not observed during any of the subsequent mating sessions Data shown are latencies to intromission and ejaculation (seconds) in animals treated either with systemic (s.c.) saline or naloxone (10 mg/kg) during 5 consecutive days (saline, n = 11; naloxone, n = 12). Data for days 1 and 5 are also presented in Figure 4. Data are presented as mean ± SEM;
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↵* indicates significant difference between treatments on the same day.




