Table 3.
Comparison of changes (%) in EPSP amplitude and PPR caused by hyperpolarization of the presynaptic mitral cells or by block of T-type channels with Z941 (10 μm)
| Control (n = 8) | Hyperpolarized (n = 8) | % change | Pre-Z941 (n = 5) | Z941 (n = 5) | % change | |
|---|---|---|---|---|---|---|
| EPSP1 (mV) | 0.76 ± 0.19 | 0.54 ± 0.15 | −28.9% | 1.28 ± 0.36 | 0.92 ± 0.27 | −28.1 |
| p < 0.0001 | p = 0.0040 | |||||
| EPSP2 (mV) | 0.33 ± 0.05 | 0.32 ± 0.05 | −3.0% | 0.34 ± 0.08 | 0.37 ± 0.07 | 8.8 |
| p = 0.6624 | p = 0.7510 | |||||
| PPR | 0.50 ± 0.07 | 0.70 ± 0.07 | 40.0% | 0.35 ± 0.08 | 0.50 ± 0.09 | 42.9 |
| p = 0.0009 | p = 0.0032 |
