Mammalian Target of Rapamycin's Distinct Roles and Effectiveness in Promoting Compensatory Axonal Sprouting in the Injured CNS

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Figure 5.
Figure 5.

Degree of tdTomato labeling at the level of medulla in various animal groups. A, Representative coronal sections of the medullary pyramid showing tdTomato labeled-CST axons 5 weeks after AAV-Cre injection (i.e., 4 weeks after pyramidotomy) in sham-operated Rosa-tdTomato (sham), pyramidotomized Rosa-tdTomato (Px only), and pyramidotomized PTENf/f;Rosa-tdTomato (Px+PTEN KO) mice. B, Quantification of total tdTomato labeled-CST axons at the medullary pyramid in each animal groups. Error bars indicate SEM. Px, Pyramidotomy. Scale bars, 100 μm.

  1. The Journal of Neuroscience vol. 34 no. 46 15347-15355
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