GABAergic Transmission to Kisspeptin Neurons Is Differentially Regulated by Time of Day and Estradiol in Female Mice

Table 4.

ANOVA FDFn,DFd and significance

Two-way ANOVA GABA sPSCs GABA mPSCs
Amplitude Frequency Amplitude Frequency
Arcuate
    Time of day F(1, 46) = 5.7* F(1, 46) = 3.4 F(1, 40) = 0.002 F(1, 40) = 4.6*
    Estradiol F(1, 46) = 14.7*** F(1, 46) = 0.3 F(1, 40) = 29.5*** F(1, 40) = 2.5
    Interaction F(1, 46) = 2.2 F(1, 46) = 3.6 F(1, 40) = 0.6 F(1, 40) = 2.0
AVPV
    Time of day F(1, 43) = 5.6* F(1, 43) = 4.3* F(1, 33) = 0.5 F(1, 33) = 4.4*
    Estradiol F(1, 43) = 1.6 F(1, 43) = 2.3 F(1, 33) = 0.2 F(1, 33) = 0.005
    Interaction F(1, 43) = 2.7 F(1, 43) = 2.7 F(1, 33) = 0.7 F(1, 33) = 4.2*
OCVm
RM ANOVA Arcuate AVPV
Baseline − GABA F(1, 37) = 28.1*** F(1, 31) = 45.0***
Estradiol −
    Time of day F(3, 37) = 2.3 F(3, 31) = 3.9**
    Interaction F(3, 37) = 2.3 F(3, 31) = 2.7
    Matching F(37, 37) = 2.4** F(31, 31) = 3.1**
  • ↵*p < 0.05;

  • ↵**p < 0.01;

  • ↵***p < 0.001.

  1. The Journal of Neuroscience vol. 34 no. 49 16296-16308
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