
Local inactivation of dorsolateral but not dorsomedial striatum with muscimol+baclofen decreased context-induced reinstatement of methamphetamine seeking. A, B, Bilateral injections of muscimol+baclofen into (B) dorsolateral striatum, but not (A) dorsomedial striatum, decreased active lever pressing (mean ± SEM) during reinstatement tests in the Methamphetamine Context but not in the Extinction Context (*different from the Vehicle Group, *p < 0.01, n = 7–12 per group). C, D, Dots indicate approximate placements (millimeters from bregma) of injector tips into the (C) dorsomedial or (D) dorsolateral striatum (Paxinos and Watson, 2005).




