Gene expression in Fos-positive and Fos-negative neurons that were FACS-isolated from dorsal striatum after context-induced reinstatement of methamphetamine. A, IEGs (Fos, FosB (total), Homer-1). B, Genes encoding NMDA receptor subunits (Grin1, Grin2a) and cannabinoid receptor (Cbr1). Exposure to the Extinction or Methamphetamine (Meth) Contexts increased gene expression in Fos-positive neurons relative to the Fos-negative neurons (*p < 0.05; #, main effect for Fos cell type; Extinction Context, n = 3–11; Methamphetamine Context, n = 7–17). See Table 2 summary for all genes analyzed.