Goal-Directed Modulation of Neural Memory Patterns: Implications for fMRI-Based Memory Detection

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Figure 4.
Figure 4.

Memory decoding trained on the explicit recognition memory task. A, Performance of memory classifiers (hits vs CRs) trained on standard recognition memory data and tested on held-out trials from the same condition (explicit memory trials, EX→EX; blue) or on trials when they were attempting to conceal their true memory state (concealed memory trials, EX→CM; green). Violin plots depict the mean AUC for ROC curves (for description of this metric, see text). Plots demonstrate that memory decoding was above chance during a standard recognition memory test (EX→EX, blue) but reduced to chance levels when participants attempted to conceal memory (EX→CM, green). AUC values are plotted for each participant's data using unique color identifiers, with lines connecting each participant's classification performance, and plot-width depicting participant density in that performance range. B, Classifiers trained and tested on each time point (2 s volume acquisition, TR) revealed similar results as in A, with above-chance decoding on standard memory trials (blue) and chance decoding on concealed memory trials (time point 4–6 s was slightly above chance). C, Maps indicating the diagnostic value that each voxel provides the classifier (importance maps) in biasing a hit choice (warm colors) or a CR choice (cool colors). Error bars in B indicate SEM. EX, Explicit memory task; CM, concealed memory task; EX→EX, classifier trained on explicit trials, tested on held-out explicit trials (4-fold cross-validation); EX→CM, classifier trained on explicit trials, tested on concealed trials.

  1. The Journal of Neuroscience vol. 35 no. 22 8531-8545
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