Zebrafish Models for the Mechanosensory Hair Cell Dysfunction in Usher Syndrome 3 Reveal That Clarin-1 Is an Essential Hair Bundle Protein

Table 2.

ZFN-targeted zebrafish clrn1mutants inherit the mutant alleles in a Mendelian ratio

F₁ breeding pair (parents)	F₂ clutch size	Number of larvae genotyped^{^a}	Genotype
F₁ breeding pair (parents)	F₂ clutch size	Number of larvae genotyped^{^a}	clrn1^+/+	clrn1^+/CWR1 or clrn1^+/CWR2	clrn1^CWR1/2^{,^b}
clrn1^+/CWR1 × clrn1^+/CWR2	198	48	13 (27%)	21 (44%)	14 (29%)
	94	50	13 (26%)	26 (52%)	11 (22%)
	265	100	31 (31%)	43 (43%)	26 (26%)

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