J.K. lacked dyspnea and awareness of amygdala stimulation-evoked apnea. J.K. was completely unaware of and displayed no dyspnea with 48 s of apnea evoked by a 47 s stimulation of the left amygdala (A), which resulted in oxygen desaturation to 87% (B). C, J.K. voluntarily held his breath for 60 s, which caused an oxygen desaturation to 91% and severe shortness of breath and dyspnea (D). E, J.K. was agnostic to repeated amygdala stimulation (5 s on and off), which first caused sustained apnea, followed by a new respiratory pattern consisting of two breaths during the 5 s without stimulation and apnea during the period of stimulation. F, Breathing during a 5 s on and 5 s off amygdala stimulation paradigm over a period of 5 min resulted in initiated breaths during the 5 s off stimulation and apnea during the periods of stimulation and resulted in a new intermittent breathing pattern. This lasted the entire period of the stimulation paradigm. J.K. was unaware of any breathing changes during this stimulation.