
DHA enhances sprouting of corticospinal axons following cervical lateral hemisection in rats. A–C, Photomicrographs of horizontal sections 1000 μm caudal to the lesion site reveal more sprouting of BDA-labeled CST collaterals (arrows) across the midline into the lesion side in the DHA-treated group compared with the vehicle-treated and sham operation group. D, E, Quantitative analysis showed a significant increase in BDA-labeled CST fibers at certain levels of the spinal cord rostral and caudal to the injury on both the lesioned and unlesioned side in DHA-treated animals (red circle) compared with the vehicle-treated animals (blue square). *p < 0.05, DHA versus the vehicle group. **p < 0.01, DHA versus the vehicle group. Scale bar, 100 μm. F–H, No significant difference was found in the number of BDA-labeled CST axons at the C1 dorsal funiculus between the DHA and vehicle-treated groups. ns, Not significant.




