Ligand Specificity and Evolution of Mammalian Musk Odor Receptors: Effect of Single Receptor Deletion on Odor Detection

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Figure 5.
Figure 5.

Behavioral responses to muscone in MOR215-1 KO mice. A, Time to find the odor source in WT C57BL/6 mice (W) and MOR215-1 KO mice (K). Each triangle depicts a single individual. Animals that failed to find muscone (left) or eugenol (right) in 5 min were plotted at 5. PG, Propylene glycol. Muscone and eugenol were serially diluted from 10−1 (10%) to 10−7 (0.00001%) in PG and from 10−1 (10%) to 10−8 (0.000001%) in mineral oil. B, Summary of odor source-exploring experiments shown in Figure 5A. Vertical axis represents the percentage of the animals that found the odor sources within 5 min. The number of animals that found the odor sources and the number of total animals examined are shown inside each bar.

  1. The Journal of Neuroscience vol. 36 no. 16 4482-4491
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