Table 2.
Significantly activated clusters of cumulative gambling in the model with serial orthogonalizationa
| Region | z Score peak | Peak MNI coordinates: right hemisphere | z Score peak | Peak MNI coordinates: left hemisphere | ||||
|---|---|---|---|---|---|---|---|---|
| x | y | z | x | y | z | |||
| Task-related activity during “Continue” trials showing a linear increase with cumulative gambling (accumulated sum) | ||||||||
| Ventral striatum extending into caudate head | 5.99 | 14 | 10 | −4 | 5.22 | −12 | 4 | −2 |
| Pre-SMA | 5.90 | 6 | 16 | 52 | ||||
| Dorsal ACC | 5.64 | 6 | 26 | 38 | ||||
| Visual area V3/V4 | 4.73 | 48 | −62 | −20 | 5.37 | −22 | −100 | 0 |
| Inferior frontal gyrus | 5.24 | 42 | 24 | 6 | 5.29 | −32 | 22 | −10 |
| Inferior parietal cortex | 5.10 | 32 | −54 | 52 | 4.24 | −46 | −36 | 42 |
| Thalamus | 5.08 | 8 | −16 | −14 | ||||
| Dorsolateral prefrontal cortex | 4.87 | 32 | 52 | 26 | 4.68 | −34 | 56 | 20 |
| Subthalamic nucleus (SVC) | 4.96 | 8 | −16 | −12 | 4.67 | −6 | −14 | −12 |
| Task related activity during “Continue” trials showing a linear decrease with cumulative gambling (accumulated sum) | ||||||||
| Inferior parietal cortex | 5.15 | −40 | −82 | 38 | ||||
| Precuneus | 3.81 | −4 | −60 | 20 | ||||
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↵aSignificant activation peaks (z score) and the corresponding stereotactic x, y, z coordinates in MNI space for cumulative gambling in the model with serially orthogonalized regressors. Results are significant at p < 0.001, uncorrected, at whole-brain level (t > 3.646), cluster extent threshold >30 voxels, cluster-level p < 0.05 FWE-corrected.
