A flash of light fails to induce late spiking in the retina. A, In vivo multiunit recordings were acquired from the retina while a light flash was presented 50 times to the ipsilateral eye. B, Top, Raw multiunit traces of five representative trials. Middle, Spike raster plots of spike responses. Bottom, Peristimulus time histograms (PSTHs) of the spike response. C, Data were pooled from five recordings from five mice. D, Mean ± SEM of the multiunit spike rates during the time windows of the preflash baseline and the V1 early and late windows of five recordings from five mice. Late spiking is absent from the retinal responses. ***p = 0.0050, t₍₄₎ = 5.58, paired t test.