Bidirectional Modulation of Intrinsic Excitability in Rat Prelimbic Cortex Neuronal Ensembles and Non-Ensembles after Operant Learning

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Figure 5.
Figure 5.

Enhanced contribution of SK channels in nonactivated population of neurons after operant learning. A, B, Example traces showing the effect of SK channel antagonism on mAHP currents in FosGFP− neurons in the test group. Summary graph shows larger SK contribution to the mAHP in day 10 FosGFP− neurons (*p < 0.05, day 1 FosGFP−: n = 10 cells/6 rats; day 10 FosGFP−: n = 9 cells/6 rats). C, Example traces showing larger effect of SK channel antagonism on repetitive firing in FosGFP− day 10 neurons from the test group. D, Summary graph showing the percentage increase in firing after SK channel antagonism in FosGFP− neurons (*p < 0.05, day 1 FosGFP−: n = 10 cells/6 rats; day 10 FosGFP−: n = 9 cells/6 rats).

  1. The Journal of Neuroscience vol. 37 no. 36 8845-8856
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