Brief Novel Visual Experience Fundamentally Changes Synaptic Plasticity in the Mouse Visual Cortex

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Figure 4.
Figure 4.

mGluR-LTP promoted by vision after DR depends on PKC activity and intact protein synthesis. A, Protein synthesis inhibitors blocked APV-unmasked LTP (filled triangles represent cycloheximide; open circles represent anisomycin; filled circles represent APV). B, PKC inhibitors blocked APV-unmasked LTP (filled triangles represent CGP 41251; open circles represent bisindolylmaleimide II; filled circles represent APV). C, PKA inhibitor did not block APV-unmasked LTP (filled circles represent APV; open circles represent PKI). D, CaMKII inhibitor blocked APV-unmasked LTP (filled circles represent APV; open circles represent AIP).

  1. The Journal of Neuroscience vol. 37 no. 39 9353-9360
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