Spinal Motor Circuit Synaptic Plasticity after Peripheral Nerve Injury Depends on Microglia Activation and a CCR2 Mechanism

Table 3.

Morphological characteristics of reconstructed motoneurons and VGLUT1 numbersa

Control Tibial ligation Sciatic ligation
Soma surface area (μm2) 3118 ± 142 2989 ± 268 2377 ± 239
Dendritic length (μm) 431 ± 28 324 ± 55 249 ± 45
Dendritic surface area (μm2) 5014 ± 292 3553 ± 920 2044 ± 364b
# of VGLUT1 contacts on soma 23.2 ± 1.0 12.6 ± 1.6b 7.0 ± 1.3b
# of VGLUT1 contacts on dendrites 71.6 ± 4.8 45.0 ± 6.7b 28.0 ± 4.8b
  • ↵aData are reported as mean ± SE; n = 4 mice, 6 motoneurons per mouse.

  • ↵bSignificant difference from controls (p < 0.05).

  1. The Journal of Neuroscience vol. 39 no. 18 3412-3433
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