Rgma-Induced Neo1 Proteolysis Promotes Neural Tube Morphogenesis

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Figure 7.
Figure 7.

Rgma depletion disrupts C divisions. A, B, Transverse sections through the hindbrain of 8–10 som control (uninjected, A) and rgma MO2-injected (B) embryos immunolabeled with anti-tubulin (MTs, cyan) and counterstained with DAPI (nuclei, red). Scale bar, 50 μm. A′–B′, Insets, Higher magnification of the boxed regions in A and B showing daughter cells (1 and 2) with the estimated position of the midbody (*). Scale bar, 10 μm. C, Percentage of cell divisions occurring at each azimuthal angle (θ). Control, n = 20 cell divisions from 4 embryos; rgma MO2, n = 26 cell divisions from 6 embryos.

  1. The Journal of Neuroscience vol. 39 no. 38 7465-7484
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