Modeling the Short-Term Dynamics of in Vivo Excitatory Spike Transmission

Table 2.

Summary of parameter estimates from the full TM-GLM

Synapse n Formula (ms) Formula (ms) Formula (ms) U
Thalamus 1 14 ± 2 410 ± 107 37 ± 12 0.29 ± 0.04
VB-Barrel 1 0.3 ± 0.003 182 ± 8 105 ± 9 0.10 ± 0.05
ANF-SBC 1 0.25 ± 0.02 67±6 71 ± 3 0.068 ± 0.006
Excitatory-RS 19 84 ± 116 215 ± 219 820 ± 745 0.46 ± 0.17
Excitatory-FS 22 72 ± 196 411 ± 459 406 ± 552 0.34 ± 0.19
  • Sample size (n), membrane time constant (Formula), depression time constant (Formula), and facilitation time constant (Formula), and release probabilities (U) for the identified and putative synapses from our three case studies and multielectrode recordings. For the cases studies, the mean ± SD is shown for the bootstrap samples. For the MEA data, the mean ± SD is shown across putative connections. In all cases, the parameters are estimated from ongoing, in vivo spiking activity.

  1. The Journal of Neuroscience vol. 40 no. 21 4185-4202
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