Stimulation speed, stepping speed and p values testing for significant entrainment in the two altDBS conditions
| alt DBS slow | puncorrected | pFDR-corrected | alt DBS fast | puncorrected | pFDR-corrected | |||
|---|---|---|---|---|---|---|---|---|
| stimSpeed | stepSpeed | stimSpeed | stepSpeed | |||||
| P01 | 1.2 | 1.12 | 0.317 | - | 0.96 | 1.07 | 0.079 | - |
| P02 | 1.8 | 1.69 | <0.001 | <0.001 | 1.44 | 1.62 | 0.039 | 0.992 |
| P03 | 1.2 | 0.87 | 0.893 | - | 0.96 | 0.87 | <0.001 | <0.001 |
| P04 | 1.2 | 0.91 | 0.845 | - | 0.96 | 0.81 | 0.744 | - |
| P05 | 1.1 | 0.89 | 0.124 | - | 0.88 | 0.92 | 0.976 | - |
| P06 | 1.2 | 1 | 0.762 | - | 0.96 | 0.98 | 0.007 | 0.032 |
| P07 | 1.1 | 1.01 | 0.875 | - | 0.88 | 1.11 | 0.738 | - |
| P08 | 1.2 | 0.87 | 0.878 | - | 0.96 | 0.86 | 0.008 | 0.032 |
| P09 | 1.5 | 1.39 | 0.841 | - | 1.2 | 1.47 | 0.728 | - |
| P10 | 1.2 | 1.21 | <0.001 | 0.001 | 0.96 | 1.31 | 0.994 | - |
-
The p values in bold highlight the patients that were significantly entrained to the altDBS pattern (assessed with Rayleigh tests). The column pFDR-corrected shows the adjusted p values after controlling for the 20 comparisons performed in this table with the false discovery rate (FDR) procedure. Significant entrainment always occurred in the condition where the stepping speed was closer to the stimulation speed. Only P02 was also entrained to altDBS in the other condition. P05 and P07 reported that when stimulation was switched off outside of this study, they did not notice an immediate deterioration of symptoms, suggesting that DBS only had weak positive effects. These two patients were not entrained to altDBS.
