This image shows growing axons of embryonic day 18.5 (E18.5) cortical neurons in mouse brain, which were eletroporated in utero at E14.5 with plasmids encoding Myo X-shRNA (marked by GFP, green) and Myc-tagged Netrin-1 (marked by anti-Myc, red). DAPI, blue. Netrin-1 promotes Myo X axonal distribution in a KIF13B-dependent way, which is crucial for axon initiation and contralateral targeting. For more information, see the article by Yu et al. (pages 9169–9185). Cover Image: Huali Yu.