Brief Sensory Deprivation Triggers Cell Type-Specific Structural and Functional Plasticity in Olfactory Bulb Neurons

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Figure 3.
Figure 3.

Brief unilateral naris occlusion decreases activity levels in bulbar excitatory neurons. A, C, Example maximum intensity projection images of bulbar M/TCs (A) or ETCs (C) visualized via SMI-32 staining, and the activity marker pS6. epl, External plexiform layer; mcl, mitral cell layer; gcl, granule cell layer; gl, glomerular layer. Arrows indicate pS6+ M/TCs (A) or ETCs (C). SMI-32+ cells located in the epl (asterisks) were not analyzed. Experimental design as in Figure 2A. B, D, Normalized pS6 intensity in M/TCs (B) or ETCs (D) from 6 sets of Ctrl and Occl mice. Empty circles represent individual cells. Different colors represent different mice. Thick line indicates mean ± SEM. ***p < 0.0001.

  1. The Journal of Neuroscience vol. 41 no. 10 2135-2151
  1. Free Access 
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