Table 1.

Vesicle exocytosis is enhanced by 1 mm cAMP^{^a}

Duration	ΔC_m Mean ± SEM	n	t test (p)
1 ms	control: 8.79 ± 1.76	6	0.2948 (NS)
	cAMP: 12.2 ± 2.57	6
2 ms	17.3 ± 1.44	12	0.2991 (NS)
	20.3 ± 1.95	23
5 ms	24.8 ± 2.27	14	0.0689 (NS)
	31.9 ± 2.72	19
10 ms	29.1 ± 2.56	12	0.0184^*
	41.2 ± 3.65	16
20 ms	31.1 ± 3.42	18	0.003^**
	48.0 ± 4.03	16
40 ms	33.2 ± 4.25	14	0.0031^**
	54.2 ± 4.80	13
60 ms	35.6 ± 3.99	16	0.0263^*
	52.4 ± 6.26	11
80 ms	38.1 ± 4.24	12	0.0168^*
	60.0 ± 7.91	8
100 ms	39.9 ± 3.11	21	<0.0001^****
	75.6 ± 7.05	22
200 ms	57.9 ± 4.36	12	0.0039^**
	87.6 ± 6.82	20
300 ms	68.2 ± 5.97	11	0.001^**
	110 ± 7.87	19
400 ms	70.0 ± 8.48	6	0.005^**
	112 ± 7.72	14
500 ms	76.8 ± 10.1	10	0.0057^**
	126 ± 10.9	17

↵^aSummary results for Figure 3B and C displaying ΔC_m responses to depolarizing pulse durations from 1 to 500 ms. Recordings were performed between 4 and 7 min after whole-cell break-in with control internal pipette solutions or with 1 mm cAMP containing internal solutions in separate groups of AII-ACs. Pulses were given in random order across different cells. ΔC_m values are listed as mean ± SEM for control and 1 mm cAMP datasets. The number of AII-AC recordings (n) and results from a Student's t test are listed.
NS (p > 0.05);
↵*p < 0.05;
↵**p < 0.001;
↵****p < 0.0001.

The Journal of Neuroscience Society for Neuroscience

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