Arcuate Nucleus Overexpression of NHLH2 Reduces Body Mass and Attenuates Obesity-Associated Anxiety/Depression-like Behavior

Table 4.

Impact of Nhlh2 hypothalamic overexpression on body mass gain and caloric intake in female micea

Parameter SCc OEc
Nhlh2 transcript (relative to control) 1.00 ± 0.32 1.38 ± 0.34*
Body mass gain (g) 9.4 ± 2.2 5.3 ± 2.0*
Caloric intake (kcal/d) 17.8 ± 3.3 13.1 ± 2.4*
  • ↵aIn all experiments, n = 10. SCc, Scrambled fed on chow; OEc, overexpression fed on chow.

  • ↵*p < 0.05 versus SCc.

  1. The Journal of Neuroscience vol. 41 no. 48 10004-10022
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