Summary of SWR alterations in AD models in vivo (A) and in vitro (B). Summary of Hermann et al. (2009); Ciupek et al. (2015); Booth et al. (2016); Gillespie et al. (2016); Iaccarino et al. (2016); Nicole et al. (2016); Witton et al. (2016); Xiao et al. (2017); Hollnagel et al. (2019); Jura et al. (2019); and Caccavano et al. (2020). C, Findings for normal aging studies are also included. Summary of Kanak et al. (2013) and Wiegand et al. (2016).