Blocking Site-Specific Cleavage of Human Tau Delays Progression of Disease-Related Phenotypes in Genetically Matched Tau-Transgenic Mice Modeling Frontotemporal Dementia

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Figure 7.
Figure 7.

Brain weights of rT1, rT2, and rT3 mice. A, A scatterplot illustrating the wet brain weights of rT1, rT2, rT3, and non-Tg (combining non-Tg littermates of rT1, rT2, and rT3 mice at the same age; for details, see Experimental design and statistical analyses) mice. B, Post hoc comparisons of brain weights at varied ages between mouse lines. p values of <0.05 are highlighted in bold. M, months of age. For detailed gender distribution and numbers of animals used, see Table 1.

  1. The Journal of Neuroscience vol. 42 no. 23 4737-4754
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