1NMPP1 blocks NRG1 dependent decrease in SW-R occurrence in the CA1 hippocampus in vitro. A, Inability of Neuregulin 1 (NRG1) to decrease SW-R occurrence in presence of 1NMPP1 in T796G slices. B, C, No effect on sharp wave length (B) or amplitude (C) by NRG1 (pink) or NRG1 + 1NMPP1 (green), compared with baseline (black) or washout (green). D, No effect of NRG1 (pink) or NRG1 + 1NMPP1 (green) on ripple power between 150 and 300 Hz compared with baseline (black) or washout (green; NRG1 n = 6 slices, 6 T796G mice; NRG1 + 1NMPP1 n = 8 slices, 8 T796G mice). Error bars indicate SEM. n.s., not significant. *p < 0.05.