CCI-injured mice show reduced firing in PVBCs in the dentate gyrus. A, A representative image of a PVBC. The biocytin-filled PVBC was imaged using confocal microscope. Axon terminals were localized in the GCL of the dentate gyrus, whereas dendrites extended into the inner molecular layer (IML), outer molecular layer (OML), and hilus. The biocytin-labeled PVBC (red) also expressed PV (purple). B, AP firing properties of PVBCs. Evoked APs and voltage responses in PVBCs from CCI and sham control mice during 1 s depolarizing (400 pA) and hyperpolarizing (−200 pA) current steps. There is reduced AP firing in the PVBC from a CCI-injured mouse. C, The summary of AP firing frequency of PVBCs from CCI and sham control mice. n indicates number of PVBCs. Data are mean ± SEM. *p < 0.05. **p < 0.01. ***p < 0.001.