Table 2.
Intrinsic properties of PVBCs in sham control and CCI injured micea
| Animal group | Sham (n = 10) | CCI (ipsilateral; n = 7) | p |
|---|---|---|---|
| RMP (mV) | −67.3 ± 1.0 | −63.9 ± 2.8 | 0.206 |
| Rin (mΩ) | 107.3 ± 8.1 | 75.5 ± 9.2* | 0.022 |
| τmembrane (ms) | 14.2 ± 0.7 | 17.3 ± 3.7 | 0.661 |
| Rheobase (pA) | 255.0 ± 33.7 | 435.7 ± 91.1 | 0.051 |
| AP threshold (mV) | −40.0 ± 1.9 | −35.7 ± 2.3 | 0.185 |
| AP amplitude (mV) | 68.5 ± 1.9 | 61.7 ± 4.4 | 0.141 |
| AP half-width (ms) | 0.52 ± 0.03 | 0.54 ± 0.03 | 0.593 |
| AP frequency (Hz) | 51.8 ± 9.4 | 17.8 ± 6.8* | 0.017 |
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↵aFor descriptions of each of the measured intrinsic properties, see Materials and Methods. n values represent number of recorded PVBCs. AP frequency was measured from APs evoked by 1 s depolarizing current steps (400 pA). RMP, Resting membrane potential; Rin, input resistance; τmembrane, membrane time constant.
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↵*p < 0.05.
