Shisa7 decreases GABA_AR burst duration and P_o. A, Representative traces of single-channel clusters of bursts elicited by 10 mm GABA in α2β3γ2L GABA_AR cotransfected with either Ctrl or Shisa7 (top), with the blue bar indicating representative bursts from both conditions (bottom). B, Bar graphs depicting mean duration, mean P_o, MCT, and MOT of single-channel bursts (Ctrl, n = 10; Shisa7, n = 12; Mann–Whitney U test, two tailed; *p = 0.05, **p = 0.005, ****p < 0.0001). Error bars indicate the SEM.