High-Resolution Tractography Protocol to Investigate the Pathways between Human Mediodorsal Thalamic Nucleus and Prefrontal Cortex

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Figure 5.
Figure 5.

Intrathalamic and extrathalamic paths of the tracts connecting MD with four cortical areas belonging to the mPFC group region. A, Streamline visualizations of the tractographies between MD (red line contour) and area 10r (yellow), area 10v (green), area s32 (blue), and area 25 (purple). The part of the cortex corresponding to each seed area is delineated, and its pial surface is highlighted in color. Each tract is coded in the corresponding color; white indicates coregistration of all four streamlines in the same voxel. Note that the four tracts remain partially coregistered (shown in white and indicated by an arrow) only near their origin in medial MD. The asterisk indicates the coronal slice from which the magnified image shown in B was taken. B, Magnified visualization of a coronal slice showing the streamlines reaching cortical area 10v. C–F, Coronal sections of both thalami at higher magnification. Tractographies were obtained from the same individual shown in Figure 2. Scale bars: A, 1 cm; E (for C–F), 1 cm. Graphic conventions and abbreviations are as in Figure 3.

  1. The Journal of Neuroscience vol. 43 no. 46 7780-7798
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