High-Resolution Tractography Protocol to Investigate the Pathways between Human Mediodorsal Thalamic Nucleus and Prefrontal Cortex

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Figure 6.
Figure 6.

Intrathalamic and extrathalamic paths of the tracts connecting MD with four cortical areas in the OrbPoPFC group region. A, Streamline visualizations of the tractographies between MD (red line contour) and area 11l (yellow), area 13l (green), area p10p (blue), and area a10p (purple). The part of the cortex corresponding to each seed area is delineated, and its pial surface is highlighted in color. Each tract is coded in the corresponding color; white indicates coregistration of all four streamlines in the same voxel. Note that the four tracts remain partially coregistered to the same voxels (shown in white and indicated by an arrow) as they traverse the gray matter of the thalamus and the anterior limb of the internal capsule. The asterisk indicates the coronal slice from which the magnified image shown in B was taken. B, Magnified visualization of a coronal slice showing some streamlines propagating radially into the middle layers of cortical area 11l. C–F, Coronal sections of both thalami at higher magnification. Tractographies were obtained from the same individual shown in Figure 2. Scale bars: A, 1 cm; E (for C–F), 1 cm. Graphic conventions and abbreviations are as in Figure 3.

  1. The Journal of Neuroscience vol. 43 no. 46 7780-7798
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