
Using procedure to link processes and behaviors to neuron types. Hypothetical results of studies using 6 different Pavlovian fear conditioning procedures (rows 1-6) that assess 4 distinct behaviors (red represents freezing; cyan represents reward seeking; green represents running; purple represents rearing) and 2 latent processes (gray represents promote avoidance; black represents serve as punisher). The 10 columns (A-J) represent 10 distinct neuron types nested in distinct brain regions. Each of the 60 cells (6 rows × 10 columns) represents a single experiment in which neuron-type activity is inhibited during a specific procedure (e.g., in cell F6, neuron Type F is inhibited during a conditioned punishment procedure). Filled cells represent that inhibiting neuron-type activity disrupts behavior or process (e.g., inhibiting activity of neuron Types A, G, I, and J disrupt cued freezing). Pattern across procedures can reveal specific (A–F), general (G and H), or complex (I and J) neuron-type contributions to processes and behaviors.




