A Cross-Species Neuroimaging Study of Sex Chromosome Dosage Effects on Human and Mouse Brain Anatomy

Table 1.

Demographics for human sample

Characteristic XY XXY Statistics XY XYY Statistics
Sample size 82 99 37 34
Age (years)
 Mean 16.41 16.38 F(1,179) = 0.001, p = 0.973 14.74 15.49 F(1,69) = 0.414, p = 0.522
 SD 5.77 4.78 4.53 5.33
 Range 6.03–24.99 6.67–25.8 5.6–24.7 7–25.9
Full scale IQ
 Mean 114.9 93.25 F(1,179) = 137, p < 2e-16** 117.62 87.15 F(1,69) = 137.6, p < 2e-16**
 SD 12.59 12.22 9.4 12.40a
 Range 83–146 64–127 97–136 62–111
Socioeconomic status (SES)
 Mean 38.39 47.34 F(1,179) = 9.543, p = 0.0023* 38.89 54.91 F(1,69) = 17.16, p = 9.57e-05**
 SD 17.87 20.6 14.47 18.04
 Range 20–95 20–120 20–70 20–95
  • *p < 0.01 and **p < 0.001 for ANOVA test of significant difference between groups (XY vs XXY or XY vs XYY).

  1. The Journal of Neuroscience vol. 43 no. 8 1321-1333
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